HCSGD entry for PLD6

1. General information

Official gene symbolPLD6
Entrez ID201164
Gene full namephospholipase D family, member 6
Other gene symbolsZUC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004519Endonuclease activityIEAmolecular_function
GO:0005741Mitochondrial outer membraneIDAcellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006655Phosphatidylglycerol biosynthetic processTASbiological_process
GO:0007126MeiosisISSbiological_process
GO:0007286Spermatid developmentISSbiological_process
GO:0008053Mitochondrial fusionIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016042Lipid catabolic processIEAbiological_process
GO:0030719P granule organizationISSbiological_process
GO:0034587PiRNA metabolic processISSbiological_process
GO:0035755Cardiolipin hydrolase activityIDAmolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043046DNA methylation involved in gamete generationISSbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43754285930.52671682310.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2651931010
GSE13712_SHEARUp0.1195387265
GSE13712_STATICDown-0.0025714951
GSE19018Up0.2181952810
GSE19899_A1Down-0.0636629708
GSE19899_A2Down-0.1896346647
PubMed_21979375_A1Up0.2137870273
PubMed_21979375_A2Up0.0826201686
GSE35957Up0.2373665409
GSE36640Up0.2983487352
GSE54402Down-0.1717505933
GSE9593Down-0.0201280291
GSE43922Up0.4866003136
GSE24585Down-0.6010858313
GSE37065Up0.0567360618
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0905293307

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT042096CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.