HCSGD entry for UNC13D


1. General information

Official gene symbolUNC13D
Entrez ID201294
Gene full nameunc-13 homolog D (C. elegans)
Other gene symbolsFHL3 HLH3 HPLH3 Munc13-4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002432Granuloma formationIEAbiological_process
GO:0002467Germinal center formationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005764LysosomeIDAcellular_component
GO:0005770Late endosomeIEAcellular_component
GO:0006909PhagocytosisIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0043304Regulation of mast cell degranulationIMPbiological_process
GO:0043320Natural killer cell degranulationIEAbiological_process
GO:0045921Positive regulation of exocytosisIMPbiological_process
GO:0051607Defense response to virusIEAbiological_process
GO:0055037Recycling endosomeIEAcellular_component
GO:0070382Exocytic vesicleIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.36762652630.93965140380.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0369297996
GSE13712_SHEARUp0.3751647926
GSE13712_STATICDown-0.0013995908
GSE19018Up0.0283242573
GSE19899_A1Down-0.0833749842
GSE19899_A2Up0.1797088941
PubMed_21979375_A1Up0.0366114750
PubMed_21979375_A2Down-0.0188940020
GSE35957Up0.1028207979
GSE36640Up0.0326868098
GSE54402Up0.0122535015
GSE9593Down-0.0072456748
GSE43922Up0.0473308452
GSE24585Up0.4429999319
GSE37065Down-0.0496344285
GSE28863_A1Down-0.0766224191
GSE28863_A2Down-0.0379000862
GSE28863_A3Up0.3767540777
GSE28863_A4Up0.1220160701
GSE48662Up0.0796440124

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017327MicroarrayFunctional MTI (Weak)18185580
hsa-miR-1MIMAT0000416MIRT023568ProteomicsFunctional MTI (Weak)18668040
hsa-let-7b-5pMIMAT0000063MIRT032278ProteomicsFunctional MTI (Weak)18668040
hsa-miR-320aMIMAT0000510MIRT044594CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.