HCSGD entry for DENND6A
1. General information
| Official gene symbol | DENND6A |
|---|---|
| Entrez ID | 201627 |
| Gene full name | DENN/MADD domain containing 6A |
| Other gene symbols | AFI1A FAM116A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0055037 | Recycling endosome | IDA | cellular_component |
| GO:2000049 | Positive regulation of cell-cell adhesion mediated by cadherin | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6788974089 | 0.0693165913 | 0.9999902473 | 0.4969986380 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2058614227 |
| GSE13712_SHEAR | Down | -0.3237669959 |
| GSE13712_STATIC | Down | -0.4351779010 |
| GSE19018 | Down | -0.1153831943 |
| GSE19899_A1 | Down | -0.2586833633 |
| GSE19899_A2 | Up | 0.1718245948 |
| PubMed_21979375_A1 | Up | 0.7874542813 |
| PubMed_21979375_A2 | Up | 0.6285158734 |
| GSE35957 | Down | -0.2080898250 |
| GSE36640 | Down | -0.8249693163 |
| GSE54402 | Up | 0.3019804705 |
| GSE9593 | Down | -0.4638252679 |
| GSE43922 | Up | 0.1284232153 |
| GSE24585 | Down | -0.1258895442 |
| GSE37065 | Up | 0.1303135403 |
| GSE28863_A1 | Up | 0.3669907658 |
| GSE28863_A2 | Down | -0.1604148059 |
| GSE28863_A3 | Down | -0.6780979680 |
| GSE28863_A4 | Down | -0.3476746802 |
| GSE48662 | Up | 0.0544692115 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT003166 | immunoprecipitaion//Microarray//qRT-PCR | Functional MTI (Weak) | 19826008 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022584 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049746 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
