HCSGD entry for EN1

1. General information

Official gene symbolEN1
Entrez ID2019
Gene full nameengrailed homeobox 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentTASbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0009953Dorsal/ventral pattern formationIEAbiological_process
GO:0009954Proximal/distal pattern formationIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030901Midbrain developmentIEAbiological_process
GO:0030902Hindbrain developmentIEAbiological_process
GO:0030917Midbrain-hindbrain boundary developmentIEAbiological_process
GO:0035115Embryonic forelimb morphogenesisIEAbiological_process
GO:0042220Response to cocaineIEAbiological_process
GO:0043473PigmentationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048666Neuron developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.36316409710.55344188670.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2869006394
GSE13712_SHEARUp0.2249285322
GSE13712_STATICDown-0.0287624778
GSE19018Down-0.0589398121
GSE19899_A1Up0.0588125553
GSE19899_A2Up0.2497931114
PubMed_21979375_A1Up0.3851161946
PubMed_21979375_A2Up0.0460922649
GSE35957Down-0.4775731466
GSE36640Up0.0864694046
GSE54402Up0.1897627606
GSE9593Down-0.1753475851
GSE43922Up0.0480791504
GSE24585Down-0.0217304099
GSE37065Down-0.0818514260
GSE28863_A1Up0.0753178115
GSE28863_A2Up0.0175425498
GSE28863_A3Up0.1890218790
GSE28863_A4Up0.0421991955
GSE48662Down-0.0637761588

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.