HCSGD entry for EPHB3

1. General information

Official gene symbolEPHB3
Entrez ID2049
Gene full nameEPH receptor B3
Other gene symbolsETK2 HEK2 TYRO6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisISSbiological_process
GO:0001655Urogenital system developmentISSbiological_process
GO:0005003Ephrin receptor activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0007411Axon guidanceISSbiological_process
GO:0007413Axonal fasciculationISSbiological_process
GO:0008046Axon guidance receptor activityIEAmolecular_function
GO:0016477Cell migrationIDAbiological_process
GO:0018108Peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0021952Central nervous system projection neuron axonogenesisIEAbiological_process
GO:0022038Corpus callosum developmentISSbiological_process
GO:0022407Regulation of cell-cell adhesionIDAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0031290Retinal ganglion cell axon guidanceIEAbiological_process
GO:0032314Regulation of Rac GTPase activityIDAbiological_process
GO:0034446Substrate adhesion-dependent cell spreadingIDAbiological_process
GO:0043088Regulation of Cdc42 GTPase activityIDAbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0048013Ephrin receptor signaling pathwayIDAbiological_process
GO:0048538Thymus developmentISSbiological_process
GO:0048546Digestive tract morphogenesisISSbiological_process
GO:0050770Regulation of axonogenesisISSbiological_process
GO:0051965Positive regulation of synapse assemblyISSbiological_process
GO:0060021Palate developmentISSbiological_process
GO:0060996Dendritic spine developmentISSbiological_process
GO:0060997Dendritic spine morphogenesisISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95102445580.26628743970.99999024730.9883315708

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1687062806
GSE13712_SHEARDown-0.0936820178
GSE13712_STATICUp0.0534781140
GSE19018Up0.0663597049
GSE19899_A1Down-0.1672189089
GSE19899_A2Down-0.3675715208
PubMed_21979375_A1Down-0.1138365689
PubMed_21979375_A2Down-0.3679084594
GSE35957Up0.0647427819
GSE36640Up0.0283069200
GSE54402Down-0.2546992699
GSE9593Down-0.0003704254
GSE43922Up0.0348162981
GSE24585Up0.2602937994
GSE37065Down-0.2006184854
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0554592816

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.