HCSGD entry for ETF1
1. General information
| Official gene symbol | ETF1 |
|---|---|
| Entrez ID | 2107 |
| Gene full name | eukaryotic translation termination factor 1 |
| Other gene symbols | D5S1995 ERF ERF1 RF1 SUP45L1 TB3-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0003747 | Translation release factor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006415 | Translational termination | TAS | biological_process |
| GO:0006449 | Regulation of translational termination | TAS | biological_process |
| GO:0006479 | Protein methylation | IDA | biological_process |
| GO:0008079 | Translation termination factor activity | TAS | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0016149 | Translation release factor activity, codon specific | IEA | molecular_function |
| GO:0043022 | Ribosome binding | TAS | molecular_function |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0427452794 | 0.9028306713 | 0.4615978261 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3028956043 |
| GSE13712_SHEAR | Up | 0.0931734506 |
| GSE13712_STATIC | Up | 0.0308360421 |
| GSE19018 | Down | -0.8706743125 |
| GSE19899_A1 | Up | 0.5220230560 |
| GSE19899_A2 | Up | 0.5589584056 |
| PubMed_21979375_A1 | Up | 0.8911796817 |
| PubMed_21979375_A2 | Up | 0.7778047506 |
| GSE35957 | Up | 0.2811574413 |
| GSE36640 | Up | 0.0197463349 |
| GSE54402 | Up | 0.6221803359 |
| GSE9593 | Up | 0.0791420058 |
| GSE43922 | Up | 0.3227862464 |
| GSE24585 | Down | -0.1623907261 |
| GSE37065 | Down | -0.0034991392 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.3536451447 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-3p | MIMAT0001340 | MIRT042497 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT045869 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046100 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | NA | hsa-miR-204 | 20369013 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
