HCSGD entry for ETFDH

1. General information

Official gene symbolETFDH
Entrez ID2110
Gene full nameelectron-transferring-flavoprotein dehydrogenase
Other gene symbolsETFQO MADD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004174Electron-transferring-flavoprotein dehydrogenase activityIDA IEAmolecular_function
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006979Response to oxidative stressIEA ISSbiological_process
GO:0009055Electron carrier activityIDAmolecular_function
GO:0016491Oxidoreductase activityIDAmolecular_function
GO:0022900Electron transport chainIDAbiological_process
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0031305Integral component of mitochondrial inner membraneIDAcellular_component
GO:0031966Mitochondrial membraneIDAcellular_component
GO:0033539Fatty acid beta-oxidation using acyl-CoA dehydrogenaseIMPbiological_process
GO:0043783Oxidoreductase activity, oxidizing metal ions with flavin as acceptorISSmolecular_function
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048038Quinone bindingIDAmolecular_function
GO:0048039Ubiquinone bindingIDAmolecular_function
GO:0050660Flavin adenine dinucleotide bindingISSmolecular_function
GO:0051536Iron-sulfur cluster bindingIEAmolecular_function
GO:00515394 iron, 4 sulfur cluster bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10122481670.20824665480.66238274920.8832194973

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3395910834
GSE13712_SHEARDown-0.0758984649
GSE13712_STATICUp0.1789869333
GSE19018Up0.4475113905
GSE19899_A1Up0.0729436138
GSE19899_A2Down-0.1121935381
PubMed_21979375_A1Down-1.1606961313
PubMed_21979375_A2Down-0.6424586979
GSE35957Up0.4483368075
GSE36640Up0.4784452225
GSE54402Down-0.5401115099
GSE9593Up0.3094774673
GSE43922Down-0.2304537320
GSE24585Up0.4825203375
GSE37065Up0.1541011455
GSE28863_A1Up0.6280874462
GSE28863_A2Up0.5913533476
GSE28863_A3Up0.0548484247
GSE28863_A4Down-0.4302008033
GSE48662Up0.2520472399

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-TriolDB04141 EXPT00697

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.