HCSGD entry for F5
1. General information
| Official gene symbol | F5 |
|---|---|
| Entrez ID | 2153 |
| Gene full name | coagulation factor V (proaccelerin, labile factor) |
| Other gene symbols | FVL PCCF RPRGL1 THPH2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002576 | Platelet degranulation | TAS | biological_process |
| GO:0005507 | Copper ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | NAS TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008015 | Blood circulation | IEA | biological_process |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0031093 | Platelet alpha granule lumen | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5926116447 | 0.8687757266 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0027154033 |
| GSE13712_SHEAR | Up | 0.0072384679 |
| GSE13712_STATIC | Up | 0.0735513699 |
| GSE19018 | Up | 0.0033373644 |
| GSE19899_A1 | Up | 0.1306997959 |
| GSE19899_A2 | Up | 0.0626626023 |
| PubMed_21979375_A1 | Up | 0.0817464314 |
| PubMed_21979375_A2 | Down | -0.1549172314 |
| GSE35957 | Up | 0.2021970571 |
| GSE36640 | Up | 0.0239611395 |
| GSE54402 | Up | 0.0627917404 |
| GSE9593 | Up | 0.0964666652 |
| GSE43922 | Up | 0.0173793961 |
| GSE24585 | Up | 0.2011682264 |
| GSE37065 | Up | 0.0776692858 |
| GSE28863_A1 | Down | -0.0066768413 |
| GSE28863_A2 | Down | -0.2059028585 |
| GSE28863_A3 | Up | 0.0268492283 |
| GSE28863_A4 | Up | 0.0358929204 |
| GSE48662 | Up | 0.0012704726 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| ART-123 | DB05777 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020806 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
