HCSGD entry for FANCA


1. General information

Official gene symbolFANCA
Entrez ID2175
Gene full nameFanconi anemia, complementation group A
Other gene symbolsFA FA-H FA1 FAA FACA FAH FANCH
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006281DNA repairTASbiological_process
GO:0006461Protein complex assemblyTASbiological_process
GO:0007140Male meiosisIEAbiological_process
GO:0008584Male gonad developmentIEAbiological_process
GO:0008585Female gonad developmentIEAbiological_process
GO:0042127Regulation of cell proliferationIEAbiological_process
GO:0043240Fanconi anaemia nuclear complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97270876110.03778306300.99999024730.3664513812

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0878754064
GSE13712_SHEARDown-0.2073243346
GSE13712_STATICDown-0.3128040674
GSE19018Down-0.0112518835
GSE19899_A1Down-0.0060122592
GSE19899_A2Down-0.4577231852
PubMed_21979375_A1Down-0.3893232994
PubMed_21979375_A2Down-0.4564890572
GSE35957Down-0.2629600868
GSE36640Down-1.1735594233
GSE54402Down-0.1127142820
GSE9593Down-0.0356518110
GSE43922Down-0.2279588281
GSE24585Up0.0139304522
GSE37065Down-0.2410022345
GSE28863_A1Down-0.0559211479
GSE28863_A2Up0.5280917958
GSE28863_A3Down-0.0879015771
GSE28863_A4Up0.0711360680
GSE48662Down-0.6772829365

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016287MicroarrayFunctional MTI (Weak)20304954
hsa-miR-17-5pMIMAT0000070MIRT050966CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.