HCSGD entry for SKA1
1. General information
| Official gene symbol | SKA1 |
|---|---|
| Entrez ID | 220134 |
| Gene full name | spindle and kinetochore associated complex subunit 1 |
| Other gene symbols | C18orf24 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000940 | Condensed chromosome outer kinetochore | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005876 | Spindle microtubule | IDA | cellular_component |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0007067 | Mitosis | IMP | biological_process |
| GO:0008017 | Microtubule binding | IDA | molecular_function |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0031110 | Regulation of microtubule polymerization or depolymerization | IDA | biological_process |
| GO:0051301 | Cell division | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8548014703 | 0.0000477375 | 0.9999902473 | 0.0114692982 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6050858238 |
| GSE13712_SHEAR | Up | 0.3236146615 |
| GSE13712_STATIC | Up | 0.1096304967 |
| GSE19018 | Up | 0.0306642284 |
| GSE19899_A1 | Down | -0.4487237650 |
| GSE19899_A2 | Down | -4.3611230087 |
| PubMed_21979375_A1 | Down | -1.9826295337 |
| PubMed_21979375_A2 | Down | -3.7682687791 |
| GSE35957 | Down | -2.3496153440 |
| GSE36640 | Down | -4.4922509676 |
| GSE54402 | Down | -0.5695416625 |
| GSE9593 | Down | -1.3184297009 |
| GSE43922 | Down | -2.4976829241 |
| GSE24585 | Down | -0.3903927969 |
| GSE37065 | Down | -0.5146357531 |
| GSE28863_A1 | Down | -0.4934217152 |
| GSE28863_A2 | Up | 1.1186126943 |
| GSE28863_A3 | Down | -0.3461754728 |
| GSE28863_A4 | Up | 0.4246314703 |
| GSE48662 | Down | -1.4084571821 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016380 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024386 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026316 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043769 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
