HCSGD entry for FGD2

1. General information

Official gene symbolFGD2
Entrez ID221472
Gene full nameFYVE, RhoGEF and PH domain containing 2
Other gene symbolsZFYVE4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleISScellular_component
GO:0005085Guanyl-nucleotide exchange factor activityISSmolecular_function
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmISScellular_component
GO:0005794Golgi apparatusISScellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0007010Cytoskeleton organizationISSbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0008360Regulation of cell shapeISSbiological_process
GO:0030027LamellipodiumISScellular_component
GO:0030036Actin cytoskeleton organizationISSbiological_process
GO:0031267Small GTPase bindingISSmolecular_function
GO:0031901Early endosome membraneIEAcellular_component
GO:0032587Ruffle membraneIEAcellular_component
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0043088Regulation of Cdc42 GTPase activityISSbiological_process
GO:0046847Filopodium assemblyISSbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74698332510.90594780970.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0031405337
GSE13712_SHEARUp0.0062696860
GSE13712_STATICDown-0.0108459313
GSE19018Up0.0341703905
GSE19899_A1Up0.0784262164
GSE19899_A2Up0.2156497978
PubMed_21979375_A1Down-0.0841420927
PubMed_21979375_A2Down-0.0411238067
GSE35957Up0.1626156648
GSE36640Up0.0262317867
GSE54402Up0.0327198897
GSE9593Down-0.0829168328
GSE43922Up0.0169064703
GSE24585Up0.2108745882
GSE37065Down-0.0811086346
GSE28863_A1Down-0.0254792895
GSE28863_A2Up0.0185673623
GSE28863_A3Up0.0883555569
GSE28863_A4Up0.0660742872
GSE48662Up0.0310307859

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017089MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.