HCSGD entry for FOXK1
1. General information
| Official gene symbol | FOXK1 |
|---|---|
| Entrez ID | 221937 |
| Gene full name | forkhead box K1 |
| Other gene symbols | FOXK1L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IBA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0007389 | Pattern specification process | IBA | biological_process |
| GO:0007517 | Muscle organ development | IEA | biological_process |
| GO:0008301 | DNA binding, bending | IBA | molecular_function |
| GO:0009790 | Embryo development | IBA | biological_process |
| GO:0009888 | Tissue development | IBA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030308 | Negative regulation of cell growth | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1091951750 | 0.7379321264 | 0.6848049083 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0927374450 |
| GSE13712_SHEAR | Up | 0.1883427065 |
| GSE13712_STATIC | Up | 0.0596926796 |
| GSE19018 | Up | 0.0238267283 |
| GSE19899_A1 | Down | -0.1841958080 |
| GSE19899_A2 | Up | 0.1445731056 |
| PubMed_21979375_A1 | Up | 0.0106676809 |
| PubMed_21979375_A2 | Down | -0.0956121313 |
| GSE35957 | Down | -0.0549714275 |
| GSE36640 | Down | -0.0323456596 |
| GSE54402 | Up | 0.0403615658 |
| GSE9593 | Up | 0.1006612073 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 1.7092922623 |
| GSE28863_A2 | Up | 1.3280954758 |
| GSE28863_A3 | Up | 0.0930453010 |
| GSE28863_A4 | Down | -0.4518846978 |
| GSE48662 | Up | 0.0380250980 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020900 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT021201 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032384 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036374 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040038 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045618 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046442 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
