HCSGD entry for TMED4
1. General information
| Official gene symbol | TMED4 |
|---|---|
| Entrez ID | 222068 |
| Gene full name | transmembrane emp24 protein transport domain containing 4 |
| Other gene symbols | ERS25 HNLF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004871 | Signal transducer activity | IMP | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3483352684 | 0.4787040006 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1549521411 |
| GSE13712_SHEAR | Down | -0.0163480721 |
| GSE13712_STATIC | Up | 0.0233157114 |
| GSE19018 | Up | 0.1546099933 |
| GSE19899_A1 | Down | -0.3769665120 |
| GSE19899_A2 | Up | 0.3417022833 |
| PubMed_21979375_A1 | Down | -0.1408335921 |
| PubMed_21979375_A2 | Down | -0.3709734368 |
| GSE35957 | Down | -0.1847310069 |
| GSE36640 | Up | 0.6692548478 |
| GSE54402 | Down | -0.2949554167 |
| GSE9593 | Up | 0.1591367774 |
| GSE43922 | Up | 0.3266724986 |
| GSE24585 | Up | 0.0697867858 |
| GSE37065 | Up | 0.1188289055 |
| GSE28863_A1 | Up | 0.0372763924 |
| GSE28863_A2 | Up | 0.2082237073 |
| GSE28863_A3 | Down | -0.6526319336 |
| GSE28863_A4 | Down | -0.0843690970 |
| GSE48662 | Up | 0.2958507150 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025119 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032125 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048520 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
