HCSGD entry for ALDH3A2

1. General information

Official gene symbolALDH3A2
Entrez ID224
Gene full namealdehyde dehydrogenase 3 family, member A2
Other gene symbolsALDH10 FALDH SLS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004029Aldehyde dehydrogenase (NAD) activityIDA IMPmolecular_function
GO:0004030Aldehyde dehydrogenase [NAD(P)+] activityIEAmolecular_function
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0006081Cellular aldehyde metabolic processIDA IEA NASbiological_process
GO:0006714Sesquiterpenoid metabolic processIDAbiological_process
GO:0007417Central nervous system developmentIMPbiological_process
GO:0007422Peripheral nervous system developmentIMPbiological_process
GO:0008544Epidermis developmentIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0033306Phytol metabolic processIMPbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0046577Long-chain-alcohol oxidase activityIDAmolecular_function
GO:0050061Long-chain-aldehyde dehydrogenase activityIDAmolecular_function
GO:0052814Medium-chain-aldehyde dehydrogenase activityIDAmolecular_function
GO:0055114Oxidation-reduction processIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00177448810.92360676270.11231309521.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0212296349
GSE13712_SHEARDown-0.1153066066
GSE13712_STATICDown-0.2870021439
GSE19018Up0.0348471949
GSE19899_A1Up0.4686321308
GSE19899_A2Up1.9908076525
PubMed_21979375_A1Up2.6852122359
PubMed_21979375_A2Up2.1114862734
GSE35957Down-0.5015062327
GSE36640Up0.3561879843
GSE54402Down-0.0707362060
GSE9593Up0.9094517698
GSE43922Up1.6221769136
GSE24585Down-0.0508359583
GSE37065Up0.1451347926
GSE28863_A1Up0.9239570152
GSE28863_A2Up0.7165069248
GSE28863_A3Down-0.6147530132
GSE28863_A4Up0.1572010584
GSE48662Up0.4248623755

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020947ProteomicsFunctional MTI (Weak)18668040
hsa-miR-7-5pMIMAT0000252MIRT025933MicroarrayFunctional MTI (Weak)19073608
hsa-miR-193b-3pMIMAT0002819MIRT041373CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23341930Sesquiterpene lactones (SLs) are plant-derived compounds that display anti-cancer effects
23341930Some SLs derivatives have a marked killing effect on cancer cells and have therefore reached clinical trials
23341930Little is known regarding the mechanism of action of SLs
Entries Per Page
Displaying Page of