HCSGD entry for MAPK15

1. General information

Official gene symbolMAPK15
Entrez ID225689
Gene full namemitogen-activated protein kinase 15
Other gene symbolsERK7 ERK8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000165MAPK cascadeIDAbiological_process
GO:0001934Positive regulation of protein phosphorylationIEAbiological_process
GO:0004707MAP kinase activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0005622IntracellularNAScellular_component
GO:0005634NucleusIEAcellular_component
GO:0007165Signal transductionIDAbiological_process
GO:0008156Negative regulation of DNA replicationIEAbiological_process
GO:0017124SH3 domain bindingNASmolecular_function
GO:0023014Signal transduction by phosphorylationIDAbiological_process
GO:0031398Positive regulation of protein ubiquitinationIEAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0035556Intracellular signal transductionIDAbiological_process
GO:0045732Positive regulation of protein catabolic processIEAbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59252302720.86703500250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0290286592
GSE13712_SHEARUp0.0331558936
GSE13712_STATICDown-0.0654531416
GSE19018Down-0.0555984904
GSE19899_A1Down-0.0154076583
GSE19899_A2Up0.1273714523
PubMed_21979375_A1Up0.0042996063
PubMed_21979375_A2Down-0.1785271988
GSE35957Up0.1370446381
GSE36640Down-0.0475070357
GSE54402Up0.0079918921
GSE9593Down-0.0057161804
GSE43922Up0.1453505541
GSE24585Up0.2044587541
GSE37065Down-0.0074925488
GSE28863_A1Down-0.0772758288
GSE28863_A2Down-0.0118329838
GSE28863_A3Up0.3505034047
GSE28863_A4Up0.1375203014
GSE48662Up0.0420076480

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.