HCSGD entry for CHSY1


1. General information

Official gene symbolCHSY1
Entrez ID22856
Gene full namechondroitin sulfate synthase 1
Other gene symbolsCHSY CSS1 ChSy-1 TPBS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0005576Extracellular regionIDAcellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030204Chondroitin sulfate metabolic processTASbiological_process
GO:0030206Chondroitin sulfate biosynthetic processIDA TASbiological_process
GO:0030279Negative regulation of ossificationIMPbiological_process
GO:0031667Response to nutrient levelsIEAbiological_process
GO:0032580Golgi cisterna membraneIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0047238Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activityIDAmolecular_function
GO:0050510N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97898743590.00749242810.99999024730.1731415277

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.0859965742
GSE13712_SHEARDown-0.3281218491
GSE13712_STATICDown-0.3135029277
GSE19018Up0.0617640176
GSE19899_A1Down-0.7352765916
GSE19899_A2Down-0.6191959149
PubMed_21979375_A1Down-0.7052266812
PubMed_21979375_A2Down-0.7533907404
GSE35957Down-0.1019811899
GSE36640Down-0.5563947092
GSE54402Down-0.3139782243
GSE9593Down-0.4470543229
GSE43922Down-0.2374907613
GSE24585Down-0.1617361950
GSE37065Down-0.0976294855
GSE28863_A1Up0.0904244046
GSE28863_A2Down-0.0061994336
GSE28863_A3Up0.6000897637
GSE28863_A4Down-0.0121707836
GSE48662Down-0.4904771895

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002605MicroarrayFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT002605MicroarrayFunctional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT002768Microarray//Microarray;OtherFunctional MTI (Weak)15685193
hsa-miR-375MIMAT0000728MIRT019774MicroarrayFunctional MTI (Weak)20215506
hsa-miR-9-5pMIMAT0000441MIRT021396SequencingFunctional MTI (Weak)20371350
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-1MIMAT0000416NAhsa-miR-115685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.