HCSGD entry for PPP6R1


1. General information

Official gene symbolPPP6R1
Entrez ID22870
Gene full nameprotein phosphatase 6, regulatory subunit 1
Other gene symbolsKIAA1115 PP6R1 SAP190 SAPS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0019903Protein phosphatase bindingIPImolecular_function
GO:0043666Regulation of phosphoprotein phosphatase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00703989590.97725596290.21907839431.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4771798157
GSE13712_SHEARDown-0.1266318701
GSE13712_STATICUp0.1128651399
GSE19018Up0.2544079478
GSE19899_A1Up0.1578773102
GSE19899_A2Up0.7496247802
PubMed_21979375_A1Up2.2688100562
PubMed_21979375_A2Up1.8224994637
GSE35957Down-0.0374322453
GSE36640Up0.2743523028
GSE54402Up0.8216791539
GSE9593Up0.0756205568
GSE43922Up0.5052004170
GSE24585Down-0.3111700688
GSE37065Down-0.1812876184
GSE28863_A1Up0.2975664543
GSE28863_A2Up0.3656272334
GSE28863_A3Up0.1948791258
GSE28863_A4Up0.0256566413
GSE48662Up0.0014193807

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1296-5pMIMAT0005794MIRT036111CLASHFunctional MTI (Weak)23622248
hsa-miR-1229-3pMIMAT0005584MIRT036308CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.