HCSGD entry for ALDOB
1. General information
| Official gene symbol | ALDOB |
|---|---|
| Entrez ID | 229 |
| Gene full name | aldolase B, fructose-bisphosphate |
| Other gene symbols | ALDB ALDO2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004332 | Fructose-bisphosphate aldolase activity | EXP IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005815 | Microtubule organizing center | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006000 | Fructose metabolic process | IMP | biological_process |
| GO:0006001 | Fructose catabolic process | TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006094 | Gluconeogenesis | TAS | biological_process |
| GO:0006096 | Glycolysis | IDA IEA TAS | biological_process |
| GO:0006116 | NADH oxidation | IDA | biological_process |
| GO:0008092 | Cytoskeletal protein binding | IDA | molecular_function |
| GO:0030388 | Fructose 1,6-bisphosphate metabolic process | IDA | biological_process |
| GO:0032781 | Positive regulation of ATPase activity | IGI | biological_process |
| GO:0034451 | Centriolar satellite | IDA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051117 | ATPase binding | IDA | molecular_function |
| GO:0070061 | Fructose binding | IMP | molecular_function |
| GO:0070072 | Vacuolar proton-transporting V-type ATPase complex assembly | IGI | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5532846016 | 0.9320781581 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0448378852 |
| GSE13712_SHEAR | Down | -0.0672240078 |
| GSE13712_STATIC | Down | -0.0203268568 |
| GSE19018 | Up | 0.1590916934 |
| GSE19899_A1 | Up | 0.1048510026 |
| GSE19899_A2 | Up | 0.0823223198 |
| PubMed_21979375_A1 | Up | 0.1613272530 |
| PubMed_21979375_A2 | Down | -0.1540302744 |
| GSE35957 | Up | 0.0838464957 |
| GSE36640 | Up | 0.0180673595 |
| GSE54402 | Up | 0.0677661045 |
| GSE9593 | Up | 0.0146408280 |
| GSE43922 | Up | 0.1090631149 |
| GSE24585 | Up | 0.1500533744 |
| GSE37065 | Up | 0.1356207865 |
| GSE28863_A1 | Up | 0.0623703291 |
| GSE28863_A2 | Down | -0.2298226963 |
| GSE28863_A3 | Up | 0.1214250297 |
| GSE28863_A4 | Up | 0.0449945127 |
| GSE48662 | Up | 0.0196672680 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1,6-Fructose Diphosphate (Linear Form) | DB02512 | EXPT00120 |
| 3-Phosphoglycerol | DB02515 | EXPT01531 |
| 1,3-Dihydroxyacetonephosphate | DB04326 | EXPT00026 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022656 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043866 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
