HCSGD entry for SNW1

1. General information

Official gene symbolSNW1
Entrez ID22938
Gene full nameSNW domain containing 1
Other gene symbolsBx42 NCOA-62 PRPF45 Prp45 SKIIP SKIP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0000398MRNA splicing, via spliceosomeIC IDA IEAbiological_process
GO:0000785ChromatinIEAcellular_component
GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0003714Transcription corepressor activityIDAmolecular_function
GO:0005112Notch bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005681Spliceosomal complexIDA IEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0007219Notch signaling pathwayTASbiological_process
GO:0008024Positive transcription elongation factor complex bIDAcellular_component
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processIEAbiological_process
GO:0016363Nuclear matrixIDAcellular_component
GO:0030511Positive regulation of transforming growth factor beta receptor signaling pathwayIDAbiological_process
GO:0035257Nuclear hormone receptor bindingIDAmolecular_function
GO:0042771Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIMPbiological_process
GO:0042809Vitamin D receptor bindingIDAmolecular_function
GO:0042974Retinoic acid receptor bindingIDAmolecular_function
GO:0043923Positive regulation by host of viral transcriptionIDA IMPbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046332SMAD bindingIDAmolecular_function
GO:0048026Positive regulation of mRNA splicing, via spliceosomeIMPbiological_process
GO:0048384Retinoic acid receptor signaling pathwayIDAbiological_process
GO:0048385Regulation of retinoic acid receptor signaling pathwayIDAbiological_process
GO:0050769Positive regulation of neurogenesisISSbiological_process
GO:0051571Positive regulation of histone H3-K4 methylationIMPbiological_process
GO:0070562Regulation of vitamin D receptor signaling pathwayIDAbiological_process
GO:0070564Positive regulation of vitamin D receptor signaling pathwayIDAbiological_process
GO:0071013Catalytic step 2 spliceosomeIDAcellular_component
GO:0071146SMAD3-SMAD4 protein complexIDAcellular_component
GO:0071300Cellular response to retinoic acidIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30928577560.84040289120.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3020036714
GSE13712_SHEARDown-0.1244654830
GSE13712_STATICUp0.0460587174
GSE19018Up0.1804644878
GSE19899_A1Up0.2184661160
GSE19899_A2Up0.1312241702
PubMed_21979375_A1Up0.2634731467
PubMed_21979375_A2Down-0.1102805982
GSE35957Down-0.4417851565
GSE36640Down-0.2663710229
GSE54402Down-0.0112919875
GSE9593Down-0.0916486810
GSE43922Up0.0323330473
GSE24585Up0.0632927810
GSE37065Up0.1244236133
GSE28863_A1Up0.2697009497
GSE28863_A2Up0.2523395019
GSE28863_A3Down-0.0563137595
GSE28863_A4Up0.1974773295
GSE48662Down-0.1862459459

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7c-5pMIMAT0000064MIRT051793CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.