HCSGD entry for PDS5B
1. General information
| Official gene symbol | PDS5B |
|---|---|
| Entrez ID | 23047 |
| Gene full name | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) |
| Other gene symbols | APRIN AS3 CG008 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000775 | Chromosome, centromeric region | TAS | cellular_component |
| GO:0000785 | Chromatin | IDA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA ISS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005694 | Chromosome | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007064 | Mitotic sister chromatid cohesion | IMP | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0042127 | Regulation of cell proliferation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8543482049 | 0.0933982827 | 0.9999902473 | 0.5819895148 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1623175129 |
| GSE13712_SHEAR | Down | -0.0481365828 |
| GSE13712_STATIC | Down | -0.0315597412 |
| GSE19018 | Down | -0.1019134180 |
| GSE19899_A1 | Up | 0.0839690481 |
| GSE19899_A2 | Down | -0.6404060773 |
| PubMed_21979375_A1 | Down | -0.2363576558 |
| PubMed_21979375_A2 | Down | -0.4332553521 |
| GSE35957 | Down | -0.2351231608 |
| GSE36640 | Down | -0.6711676991 |
| GSE54402 | Down | -0.1812348905 |
| GSE9593 | Down | -0.1883492307 |
| GSE43922 | Down | -0.3164082567 |
| GSE24585 | Up | 0.1417729436 |
| GSE37065 | Up | 0.1327473551 |
| GSE28863_A1 | Up | 0.6904840971 |
| GSE28863_A2 | Up | 0.5308313496 |
| GSE28863_A3 | Down | -0.2090605248 |
| GSE28863_A4 | Down | -0.0182256177 |
| GSE48662 | Down | -0.2148262321 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-27a-3p | MIMAT0000084 | MIRT007124 | Luciferase reporter assay | Functional MTI | 23451058 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049126 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
