HCSGD entry for FLI1
1. General information
| Official gene symbol | FLI1 |
|---|---|
| Entrez ID | 2313 |
| Gene full name | Friend leukemia virus integration 1 |
| Other gene symbols | EWSR2 SIC-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007599 | Hemostasis | TAS | biological_process |
| GO:0009887 | Organ morphogenesis | TAS | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9231011930 | 0.0941869306 | 0.9999902473 | 0.5846837303 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2481255522 |
| GSE13712_SHEAR | Up | 0.0381742544 |
| GSE13712_STATIC | Down | -0.1262469553 |
| GSE19018 | Down | -0.1299371760 |
| GSE19899_A1 | Down | -0.0855153259 |
| GSE19899_A2 | Up | 0.1756669659 |
| PubMed_21979375_A1 | Down | -0.3206235236 |
| PubMed_21979375_A2 | Down | -0.3635941827 |
| GSE35957 | Up | 0.5551352680 |
| GSE36640 | Down | -0.4021577343 |
| GSE54402 | Up | 0.1296528890 |
| GSE9593 | Up | 0.0184442462 |
| GSE43922 | Up | 0.0244339741 |
| GSE24585 | Down | -0.8676869292 |
| GSE37065 | Up | 0.0441819094 |
| GSE28863_A1 | Down | -0.0736972361 |
| GSE28863_A2 | Down | -0.0967578183 |
| GSE28863_A3 | Down | -0.2401399823 |
| GSE28863_A4 | Up | 0.1263111313 |
| GSE48662 | Down | -0.1665287284 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT004496 | qRT-PCR//Luciferase reporter assay//Western blot | Functional MTI | 20382729 |
| hsa-miR-145-5p | MIMAT0000437 | MIRT004496 | Luciferase reporter assay//Northern blot//qRT-PCR//Western blot | Functional MTI | 20737575 |
| hsa-miR-145-5p | MIMAT0000437 | MIRT004496 | Luciferase reporter assay//Western blot | Functional MTI | 21217773 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT005349 | Western blot | Non-Functional MTI | 18950466 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT005349 | Proteomics | Functional MTI (Weak) | 20584899 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT023015 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
