HCSGD entry for CYFIP1
1. General information
| Official gene symbol | CYFIP1 |
|---|---|
| Entrez ID | 23191 |
| Gene full name | cytoplasmic FMR1 interacting protein 1 |
| Other gene symbols | P140SRA-1 SHYC SRA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | ISS | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005845 | MRNA cap binding complex | IEA ISS | cellular_component |
| GO:0008360 | Regulation of cell shape | IEA | biological_process |
| GO:0030027 | Lamellipodium | IEA ISS | cellular_component |
| GO:0030032 | Lamellipodium assembly | IEA ISS | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0031529 | Ruffle organization | ISS | biological_process |
| GO:0043005 | Neuron projection | IEA ISS | cellular_component |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0048365 | Rac GTPase binding | ISS | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IEA ISS | cellular_component |
| GO:0048675 | Axon extension | IMP | biological_process |
| GO:0051015 | Actin filament binding | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2831488241 | 0.4507432810 | 0.9820061520 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0649573704 |
| GSE13712_SHEAR | Down | -0.0957165073 |
| GSE13712_STATIC | Down | -0.3095105862 |
| GSE19018 | Up | 0.8799114675 |
| GSE19899_A1 | Down | -0.4207508439 |
| GSE19899_A2 | Up | 0.3695770518 |
| PubMed_21979375_A1 | Down | -0.0335476616 |
| PubMed_21979375_A2 | Up | 0.5022896311 |
| GSE35957 | Up | 0.1113172922 |
| GSE36640 | Down | -0.0054950450 |
| GSE54402 | Up | 0.0438598159 |
| GSE9593 | Up | 0.0737028993 |
| GSE43922 | Up | 0.0015475014 |
| GSE24585 | Up | 0.0217461241 |
| GSE37065 | Down | -0.2487235647 |
| GSE28863_A1 | Up | 0.5228297555 |
| GSE28863_A2 | Up | 0.3907446558 |
| GSE28863_A3 | Down | -0.2197101165 |
| GSE28863_A4 | Down | -0.0350263259 |
| GSE48662 | Down | -0.3918875420 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020537 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041300 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042272 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045329 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
