HCSGD entry for GANAB


1. General information

Official gene symbolGANAB
Entrez ID23193
Gene full nameglucosidase, alpha; neutral AB
Other gene symbolsG2AN GLUII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004553Hydrolase activity, hydrolyzing O-glycosyl compoundsIEAmolecular_function
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005975Carbohydrate metabolic processIEAbiological_process
GO:0006457Protein foldingTASbiological_process
GO:0017177Glucosidase II complexIEAcellular_component
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0033919Glucan 1,3-alpha-glucosidase activityIEAmolecular_function
GO:0042470MelanosomeIEAcellular_component
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95683044340.01853163250.99999024730.2666376297

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1894112589
GSE13712_SHEARDown-0.4162199120
GSE13712_STATICDown-0.3985218821
GSE19018Up0.4280917192
GSE19899_A1Down-0.5751456179
GSE19899_A2Down-0.3424974796
PubMed_21979375_A1Down-0.8870593038
PubMed_21979375_A2Down-1.2941388067
GSE35957Down-0.4363301876
GSE36640Down-0.3336563670
GSE54402Down-0.1194059061
GSE9593Up0.2606472474
GSE43922Down-0.2740499952
GSE24585Down-0.0712753570
GSE37065Down-0.2405480901
GSE28863_A1Up0.0950214175
GSE28863_A2Down-0.0050985125
GSE28863_A3Down-0.3285933540
GSE28863_A4Down-0.0209245897
GSE48662Up0.4697652856

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MiglitolDB00491 APRD01117

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1296-5pMIMAT0005794MIRT036101CLASHFunctional MTI (Weak)23622248
hsa-miR-93-3pMIMAT0004509MIRT038734CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040196CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041824CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043197CLASHFunctional MTI (Weak)23622248
hsa-miR-125b-5pMIMAT0000423MIRT046015CLASHFunctional MTI (Weak)23622248
hsa-miR-23b-3pMIMAT0000418MIRT046294CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046817CLASHFunctional MTI (Weak)23622248
hsa-miR-181b-5pMIMAT0000257MIRT047273CLASHFunctional MTI (Weak)23622248
hsa-miR-181a-5pMIMAT0000256MIRT047329CLASHFunctional MTI (Weak)23622248
hsa-miR-34a-5pMIMAT0000255MIRT047360CLASHFunctional MTI (Weak)23622248
hsa-miR-107MIMAT0000104MIRT048291CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049013CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050974CLASHFunctional MTI (Weak)23622248
hsa-miR-3619-5pMIMAT0017999MIRT052860CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.