HCSGD entry for FAF2
1. General information
| Official gene symbol | FAF2 |
|---|---|
| Entrez ID | 23197 |
| Gene full name | Fas associated factor family member 2 |
| Other gene symbols | ETEA UBXD8 UBXN3B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005811 | Lipid particle | IDA | cellular_component |
| GO:0006986 | Response to unfolded protein | IEA | biological_process |
| GO:0031625 | Ubiquitin protein ligase binding | IDA | molecular_function |
| GO:0034098 | Cdc48p-Npl4p-Ufd1p AAA ATPase complex | IDA | cellular_component |
| GO:0034389 | Lipid particle organization | IMP | biological_process |
| GO:0035473 | Lipase binding | IDA | molecular_function |
| GO:0043086 | Negative regulation of catalytic activity | IDA | biological_process |
| GO:0043130 | Ubiquitin binding | IDA | molecular_function |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
| GO:0055102 | Lipase inhibitor activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0263048136 | 0.9125736636 | 0.3785247817 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0417412728 |
| GSE13712_SHEAR | Up | 0.2513037895 |
| GSE13712_STATIC | Up | 0.3075501902 |
| GSE19018 | Down | -0.1272104198 |
| GSE19899_A1 | Up | 0.4672988524 |
| GSE19899_A2 | Up | 0.8027395059 |
| PubMed_21979375_A1 | Up | 0.7401720097 |
| PubMed_21979375_A2 | Up | 1.5627466000 |
| GSE35957 | Down | -0.0502033557 |
| GSE36640 | Up | 0.5225713853 |
| GSE54402 | Up | 0.5531458425 |
| GSE9593 | Up | 0.1144601602 |
| GSE43922 | Up | 0.4403474357 |
| GSE24585 | Up | 0.2125823202 |
| GSE37065 | Down | -0.0874662115 |
| GSE28863_A1 | Up | 0.1664335125 |
| GSE28863_A2 | Up | 0.0038555509 |
| GSE28863_A3 | Down | -0.3050016464 |
| GSE28863_A4 | Down | -0.3415933035 |
| GSE48662 | Down | -0.4712992187 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028605 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041330 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045457 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
