HCSGD entry for PACS2
1. General information
| Official gene symbol | PACS2 |
|---|---|
| Entrez ID | 23241 |
| Gene full name | phosphofurin acidic cluster sorting protein 2 |
| Other gene symbols | PACS-2 PACS1L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0072661 | Protein targeting to plasma membrane | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2535682991 | 0.6201167091 | 0.9433803279 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1577510979 |
| GSE13712_SHEAR | Down | -0.2099867492 |
| GSE13712_STATIC | Down | -0.2600770568 |
| GSE19018 | Down | -0.0916955311 |
| GSE19899_A1 | Up | 0.0110510239 |
| GSE19899_A2 | Up | 0.1279580803 |
| PubMed_21979375_A1 | Up | 0.2451662284 |
| PubMed_21979375_A2 | Up | 1.1006195738 |
| GSE35957 | Down | -0.0677268328 |
| GSE36640 | Up | 0.3809090171 |
| GSE54402 | Up | 0.0737001538 |
| GSE9593 | Up | 0.2358820971 |
| GSE43922 | Up | 0.0582446817 |
| GSE24585 | Down | -0.0885098955 |
| GSE37065 | Down | -0.2630214155 |
| GSE28863_A1 | Down | -0.2914459409 |
| GSE28863_A2 | Down | -0.0316270204 |
| GSE28863_A3 | Up | 0.2785552087 |
| GSE28863_A4 | Up | 0.2128666965 |
| GSE48662 | Up | 0.6793496368 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023894 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046818 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051538 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
