HCSGD entry for LPHN2
1. General information
| Official gene symbol | LPHN2 |
|---|---|
| Entrez ID | 23266 |
| Gene full name | latrophilin 2 |
| Other gene symbols | CIRL2 CL2 LEC1 LPHH1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | NAS | biological_process |
| GO:0007218 | Neuropeptide signaling pathway | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA NAS | cellular_component |
| GO:0016524 | Latrotoxin receptor activity | NAS | molecular_function |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9624617492 | 0.0437679230 | 0.9999902473 | 0.3935823369 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1883533135 |
| GSE13712_SHEAR | Up | 0.2023892251 |
| GSE13712_STATIC | Down | -0.0676413852 |
| GSE19018 | Down | -0.3524443446 |
| GSE19899_A1 | Up | 0.0514533801 |
| GSE19899_A2 | Down | -0.0504061848 |
| PubMed_21979375_A1 | Down | -0.2959748636 |
| PubMed_21979375_A2 | Down | -0.4459451841 |
| GSE35957 | Up | 0.2606460092 |
| GSE36640 | Down | -0.2522069588 |
| GSE54402 | Down | -0.8944204424 |
| GSE9593 | Down | -0.3354073151 |
| GSE43922 | Down | -0.4913176631 |
| GSE24585 | Down | -0.2927447021 |
| GSE37065 | Up | 0.6320545244 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0085021114 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019421 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030100 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031293 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037851 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040933 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7i-5p | MIMAT0000415 | MIRT046545 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046871 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052124 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 9434634 | Two different fibroblast lines (CL1; CL2) at the fourth subculture were passaged up to replicative senescence to model aging processes in vitro |
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