HCSGD entry for UFL1
1. General information
| Official gene symbol | UFL1 |
|---|---|
| Entrez ID | 23376 |
| Gene full name | UFM1-specific ligase 1 |
| Other gene symbols | KIAA0776 Maxer NLBP RCAD RP3-393D12.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0031397 | Negative regulation of protein ubiquitination | IDA | biological_process |
| GO:0032088 | Negative regulation of NF-kappaB transcription factor activity | IMP | biological_process |
| GO:0034976 | Response to endoplasmic reticulum stress | IDA | biological_process |
| GO:0071568 | UFM1 conjugating enzyme activity | IDA | molecular_function |
| GO:0071569 | Protein ufmylation | IDA IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9355408837 | 0.1052240188 | 0.9999902473 | 0.6214048463 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0162082725 |
| GSE13712_SHEAR | Up | 0.0322448851 |
| GSE13712_STATIC | Up | 0.1122093548 |
| GSE19018 | Up | 0.0594500099 |
| GSE19899_A1 | Down | -0.3767150332 |
| GSE19899_A2 | Down | -0.2738658443 |
| PubMed_21979375_A1 | Down | -0.9081601253 |
| PubMed_21979375_A2 | Down | -0.2524614949 |
| GSE35957 | Down | -0.0919456197 |
| GSE36640 | Up | 0.1962060737 |
| GSE54402 | Down | -0.2348311142 |
| GSE9593 | Down | -0.1731424458 |
| GSE43922 | Down | -0.4174977214 |
| GSE24585 | Up | 0.1168395718 |
| GSE37065 | Up | 0.0257997320 |
| GSE28863_A1 | Up | 0.0111728294 |
| GSE28863_A2 | Up | 0.3014287472 |
| GSE28863_A3 | Down | -0.4131097143 |
| GSE28863_A4 | Down | -0.0507758742 |
| GSE48662 | Down | -0.1534289948 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001543 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
