HCSGD entry for TRAM1
1. General information
| Official gene symbol | TRAM1 |
|---|---|
| Entrez ID | 23471 |
| Gene full name | translocation associated membrane protein 1 |
| Other gene symbols | PNAS8 TRAM TRAMP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006613 | Cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9754784469 | 0.0019269291 | 0.9999902473 | 0.0846848435 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0957749143 |
| GSE13712_SHEAR | Down | -0.1173121971 |
| GSE13712_STATIC | Up | 0.0325316576 |
| GSE19018 | Up | 0.0624000193 |
| GSE19899_A1 | Down | -0.5733680668 |
| GSE19899_A2 | Down | -0.5723928576 |
| PubMed_21979375_A1 | Down | -1.0235601089 |
| PubMed_21979375_A2 | Down | -0.5843313263 |
| GSE35957 | Up | 0.4154641978 |
| GSE36640 | Up | 1.1586419489 |
| GSE54402 | Down | -0.4088071603 |
| GSE9593 | Up | 0.1638963397 |
| GSE43922 | Down | -0.4093413938 |
| GSE24585 | Down | -0.1514622822 |
| GSE37065 | Down | -0.1130575035 |
| GSE28863_A1 | Down | -1.0950693288 |
| GSE28863_A2 | Down | -1.0339975032 |
| GSE28863_A3 | Down | -0.6045451110 |
| GSE28863_A4 | Down | -0.9870754640 |
| GSE48662 | Down | -0.3736892949 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001493 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028950 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048770 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
