HCSGD entry for GSPT2
1. General information
| Official gene symbol | GSPT2 |
|---|---|
| Entrez ID | 23708 |
| Gene full name | G1 to S phase transition 2 |
| Other gene symbols | ERF3B GST2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006415 | Translational termination | TAS | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6507786976 | 0.1497733559 | 0.9999902473 | 0.7482591384 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0276653763 |
| GSE13712_SHEAR | Down | -0.6836340691 |
| GSE13712_STATIC | Down | -0.2851165247 |
| GSE19018 | Down | -0.2375027000 |
| GSE19899_A1 | Down | -0.1318341657 |
| GSE19899_A2 | Up | 0.0417965847 |
| PubMed_21979375_A1 | Up | 0.1145770408 |
| PubMed_21979375_A2 | Up | 0.1956923285 |
| GSE35957 | Up | 0.1952850318 |
| GSE36640 | Up | 0.4100542740 |
| GSE54402 | Up | 0.1110884919 |
| GSE9593 | Down | -0.0057370727 |
| GSE43922 | Up | 0.0150602905 |
| GSE24585 | Up | 0.0940179028 |
| GSE37065 | Up | 0.0888348439 |
| GSE28863_A1 | Up | 0.0904539283 |
| GSE28863_A2 | Up | 0.2020963053 |
| GSE28863_A3 | Down | -0.8325228820 |
| GSE28863_A4 | Down | -0.1203700987 |
| GSE48662 | Down | -0.2837178086 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029919 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
