HCSGD entry for EID1
1. General information
| Official gene symbol | EID1 |
|---|---|
| Entrez ID | 23741 |
| Gene full name | EP300 interacting inhibitor of differentiation 1 |
| Other gene symbols | C15orf3 CRI1 EID-1 IRO45620 PTD014 RBP21 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0003714 | Transcription corepressor activity | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IPI | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0030154 | Cell differentiation | IDA | biological_process |
| GO:0035034 | Histone acetyltransferase regulator activity | IDA | molecular_function |
| GO:0035035 | Histone acetyltransferase binding | IDA | molecular_function |
| GO:0035065 | Regulation of histone acetylation | IDA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0996493104 | 0.9076817712 | 0.6588426493 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0373577434 |
| GSE13712_SHEAR | Up | 0.0182817731 |
| GSE13712_STATIC | Up | 0.1496053608 |
| GSE19018 | Up | 0.2285730290 |
| GSE19899_A1 | Down | -0.0912047354 |
| GSE19899_A2 | Up | 0.0632653915 |
| PubMed_21979375_A1 | Down | -0.3779888454 |
| PubMed_21979375_A2 | Down | -0.0330627882 |
| GSE35957 | Up | 0.4165503900 |
| GSE36640 | Down | -0.0761107688 |
| GSE54402 | Down | -0.0780589058 |
| GSE9593 | Up | 0.0783683633 |
| GSE43922 | Down | -0.0357192142 |
| GSE24585 | Down | -0.0190110557 |
| GSE37065 | Down | -0.0461354573 |
| GSE28863_A1 | Up | 0.6683649397 |
| GSE28863_A2 | Up | 0.7092010680 |
| GSE28863_A3 | Up | 0.4916037580 |
| GSE28863_A4 | Up | 0.2775856007 |
| GSE48662 | Up | 0.0794583362 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-138-5p | MIMAT0000430 | MIRT005487 | Luciferase reporter assay//qRT-PCR//Western blot//Quantitative proteomic approach | Functional MTI | 20486779 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23466301 | In particular, the expression levels of 9 genes, HSP90B1, EID1, ATP2B4, DDAH1, PRNP, RAB1A, PGS5, TM4SF1 and SSR3, gradually increased during senescence |
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