HCSGD entry for SPDYA


1. General information

Official gene symbolSPDYA
Entrez ID245711
Gene full namespeedy/RINGO cell cycle regulator family member A
Other gene symbolsRINGO3 RINGOA SPDY1 SPY1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleIDAbiological_process
GO:0005634NucleusIDAcellular_component
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0007140Male meiosisIEA ISSbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0008284Positive regulation of cell proliferationIDAbiological_process
GO:0019901Protein kinase bindingIEA IPImolecular_function
GO:0045737Positive regulation of cyclin-dependent protein kinase activityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31287986400.89246848520.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0646889511
GSE13712_SHEARDown-0.0769066818
GSE13712_STATICUp0.1207439063
GSE19018Down-0.0872482636
GSE19899_A1Up0.0986204100
GSE19899_A2Up0.1117368837
PubMed_21979375_A1Up0.7699724089
PubMed_21979375_A2Up0.2034378484
GSE35957Up0.0337628015
GSE36640Up0.0738509682
GSE54402Down-0.1607269814
GSE9593Up0.0916668859
GSE43922Up0.0191952488
GSE24585Up0.4121576010
GSE37065Up0.0967207303
GSE28863_A1Up0.0599844296
GSE28863_A2Up0.3049621656
GSE28863_A3Down-0.1153466015
GSE28863_A4Down-0.1552207796
GSE48662Down-0.0364571878

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018986MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.