HCSGD entry for FSHB

1. General information

Official gene symbolFSHB
Entrez ID2488
Gene full namefollicle stimulating hormone, beta polypeptide
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005179Hormone activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionNAS TAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006701Progesterone biosynthetic processTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007179Transforming growth factor beta receptor signaling pathwayIEPbiological_process
GO:0007292Female gamete generationTASbiological_process
GO:0007565Female pregnancyTASbiological_process
GO:0008284Positive regulation of cell proliferationNASbiological_process
GO:0016486Peptide hormone processingTASbiological_process
GO:0030335Positive regulation of cell migrationNASbiological_process
GO:0042699Follicle-stimulating hormone signaling pathwayIEAbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0045670Regulation of osteoclast differentiationIEAbiological_process
GO:0045780Positive regulation of bone resorptionIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterNASbiological_process
GO:0060011Sertoli cell proliferationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83590069910.40289677060.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0417714477
GSE13712_SHEARDown-0.1453653613
GSE13712_STATICUp0.2066944238
GSE19018Up0.0882204752
GSE19899_A1Down-0.1918303694
GSE19899_A2Up0.0193110276
PubMed_21979375_A1Up0.1358187913
PubMed_21979375_A2Down-0.0687361887
GSE35957Up0.0729612095
GSE36640Down-0.0277070693
GSE54402Up0.1094414770
GSE9593Up0.2517904517
GSE43922Up0.0115638150
GSE24585Up0.0844873251
GSE37065Up0.0202951555
GSE28863_A1Down-0.1958784779
GSE28863_A2Down-0.1233709037
GSE28863_A3Up0.0991331233
GSE28863_A4Down-0.3429537225
GSE48662Down-0.0641789931

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.