HCSGD entry for PLA2G4F
1. General information
| Official gene symbol | PLA2G4F |
|---|---|
| Entrez ID | 255189 |
| Gene full name | phospholipase A2, group IVF |
| Other gene symbols | PLA2G4FZ |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001516 | Prostaglandin biosynthetic process | IEA | biological_process |
| GO:0004620 | Phospholipase activity | IEA | molecular_function |
| GO:0004622 | Lysophospholipase activity | IEA | molecular_function |
| GO:0005765 | Lysosomal membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0008152 | Metabolic process | IEA | biological_process |
| GO:0009395 | Phospholipid catabolic process | IEA | biological_process |
| GO:0031982 | Vesicle | IEA | cellular_component |
| GO:0032587 | Ruffle membrane | IEA | cellular_component |
| GO:0036148 | Phosphatidylglycerol acyl-chain remodeling | TAS | biological_process |
| GO:0036149 | Phosphatidylinositol acyl-chain remodeling | TAS | biological_process |
| GO:0036150 | Phosphatidylserine acyl-chain remodeling | TAS | biological_process |
| GO:0036151 | Phosphatidylcholine acyl-chain remodeling | TAS | biological_process |
| GO:0036152 | Phosphatidylethanolamine acyl-chain remodeling | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0047498 | Calcium-dependent phospholipase A2 activity | IEA | molecular_function |
| GO:0050482 | Arachidonic acid secretion | IEA | biological_process |
| GO:0071236 | Cellular response to antibiotic | IEA | biological_process |
| GO:0071407 | Cellular response to organic cyclic compound | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8255945291 | 0.6052640439 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1547490257 |
| GSE13712_SHEAR | Up | 0.0591196081 |
| GSE13712_STATIC | Down | -0.1087225324 |
| GSE19018 | Up | 0.1625181246 |
| GSE19899_A1 | Up | 0.0113441646 |
| GSE19899_A2 | Up | 0.0414241608 |
| PubMed_21979375_A1 | Down | -0.0590445758 |
| PubMed_21979375_A2 | Down | -0.1544117046 |
| GSE35957 | Up | 0.0871407692 |
| GSE36640 | Down | -0.0612179525 |
| GSE54402 | Down | -0.1198708882 |
| GSE9593 | Up | 0.0228406078 |
| GSE43922 | Up | 0.1157561728 |
| GSE24585 | Down | -0.0819161669 |
| GSE37065 | Up | 0.0249678469 |
| GSE28863_A1 | Down | -0.1049151253 |
| GSE28863_A2 | Down | -0.0885807351 |
| GSE28863_A3 | Up | 0.2754575260 |
| GSE28863_A4 | Up | 0.0559246630 |
| GSE48662 | Up | 0.0818996232 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT043457 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-326 | MIMAT0000756 | MIRT043622 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99b-5p | MIMAT0000689 | MIRT044179 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045727 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046020 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047465 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047586 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048985 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-2116-3p | MIMAT0011161 | MIRT052654 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
