HCSGD entry for GABRA2

1. General information

Official gene symbolGABRA2
Entrez ID2555
Gene full namegamma-aminobutyric acid (GABA) A receptor, alpha 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001505Regulation of neurotransmitter levelsIMPbiological_process
GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0006811Ion transportIEAbiological_process
GO:0006821Chloride transportIEAbiological_process
GO:0006836Neurotransmitter transportIMPbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIEA IMPbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008503Benzodiazepine receptor activityIMPmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030285Integral component of synaptic vesicle membraneIDAcellular_component
GO:0030424AxonIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00014643440.97452878690.03507699121.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1601320906
GSE13712_SHEARUp0.0321843405
GSE13712_STATICDown-0.0219364114
GSE19018Down-0.0281239279
GSE19899_A1Up4.7566595113
GSE19899_A2Up6.8836597540
PubMed_21979375_A1Up5.7073289633
PubMed_21979375_A2Up6.8778543023
GSE35957Up0.0628817988
GSE36640Down-0.0673700736
GSE54402Up4.0885491417
GSE9593Up0.0932855446
GSE43922Up5.7547288574
GSE24585Down-0.0864024055
GSE37065Up0.0123538352
GSE28863_A1Down-0.3159658753
GSE28863_A2Up0.1368670680
GSE28863_A3Up0.1085216508
GSE28863_A4Down-0.0376334390
GSE48662Up0.0328245310

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.