HCSGD entry for GABRA4

1. General information

Official gene symbolGABRA4
Entrez ID2557
Gene full namegamma-aminobutyric acid (GABA) A receptor, alpha 4
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007417Central nervous system developmentIEAbiological_process
GO:0008503Benzodiazepine receptor activityTASmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
GO:2001023Regulation of response to drugIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21063713000.85640991220.88449250401.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0469793507
GSE13712_SHEARUp0.0629607193
GSE13712_STATICDown-0.0753626592
GSE19018Up0.1905202860
GSE19899_A1Up0.1503310270
GSE19899_A2Down-0.1461136715
PubMed_21979375_A1Up0.7277294508
PubMed_21979375_A2Up0.5459101162
GSE35957Up0.0473014163
GSE36640Down-0.8195424183
GSE54402Up0.6799344596
GSE9593Up0.0727447582
GSE43922Down-0.1155525439
GSE24585Up0.4100824991
GSE37065Down-0.0428582515
GSE28863_A1Down-0.0782992065
GSE28863_A2Up0.0056821146
GSE28863_A3Up0.1518504985
GSE28863_A4Up0.0469251221
GSE48662Down-0.0167994863

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.