HCSGD entry for GABRG3

1. General information

Official gene symbolGABRG3
Entrez ID2567
Gene full namegamma-aminobutyric acid (GABA) A receptor, gamma 3
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0006821Chloride transportIEAbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0042493Response to drugIEAbiological_process
GO:0045202SynapseIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65219109080.91702509780.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0438681586
GSE13712_SHEARUp0.0191900745
GSE13712_STATICDown-0.0233855660
GSE19018Up0.0745916482
GSE19899_A1Up0.0802895876
GSE19899_A2Up0.0150100918
PubMed_21979375_A1Up0.0150013610
PubMed_21979375_A2Up0.0591094097
GSE35957Up0.1554490785
GSE36640Up0.0774147550
GSE54402Down-0.0098135154
GSE9593Up0.2075692817
GSE43922Up0.1610938386
GSE24585Down-0.0749421297
GSE37065Down-0.0511845278
GSE28863_A1Down-0.0426481661
GSE28863_A2Up0.0872411908
GSE28863_A3Up0.1951867374
GSE28863_A4Up0.0280686146
GSE48662Down-0.0489227158

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030026MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.