HCSGD entry for GAMT
1. General information
| Official gene symbol | GAMT |
|---|---|
| Entrez ID | 2593 |
| Gene full name | guanidinoacetate N-methyltransferase |
| Other gene symbols | PIG2 TP53I2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006600 | Creatine metabolic process | TAS | biological_process |
| GO:0006601 | Creatine biosynthetic process | IDA IEA | biological_process |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008168 | Methyltransferase activity | TAS | molecular_function |
| GO:0009887 | Organ morphogenesis | IEA | biological_process |
| GO:0030731 | Guanidinoacetate N-methyltransferase activity | IMP | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0040014 | Regulation of multicellular organism growth | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4480324988 | 0.2966020934 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0488849036 |
| GSE13712_SHEAR | Down | -0.7594435654 |
| GSE13712_STATIC | Down | -0.6044847715 |
| GSE19018 | Up | 0.1103359808 |
| GSE19899_A1 | Down | -0.0447808635 |
| GSE19899_A2 | Up | 0.7095172131 |
| PubMed_21979375_A1 | Down | -0.1450860867 |
| PubMed_21979375_A2 | Up | 0.2639185709 |
| GSE35957 | Down | -0.1785955109 |
| GSE36640 | Up | 0.1950477138 |
| GSE54402 | Up | 0.0215024293 |
| GSE9593 | Up | 0.3546445440 |
| GSE43922 | Up | 0.0019138910 |
| GSE24585 | Down | -0.0351098664 |
| GSE37065 | Down | -0.1227766387 |
| GSE28863_A1 | Down | -0.1543562140 |
| GSE28863_A2 | Down | -0.2690860338 |
| GSE28863_A3 | Up | 0.0526184749 |
| GSE28863_A4 | Down | -0.0032808498 |
| GSE48662 | Up | 0.6012188245 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Guanidine | DB00536 | APRD01008 | EXPT01546 |
| S-Adenosyl-L-Homocysteine | DB01752 | EXPT02842 |
| N-[Amino(Imino)Methyl]Glycine | DB02751 | EXPT02364 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
