HCSGD entry for PARS2


1. General information

Official gene symbolPARS2
Entrez ID25973
Gene full nameprolyl-tRNA synthetase 2, mitochondrial (putative)
Other gene symbolsMT-PRORS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004827Proline-tRNA ligase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005759Mitochondrial matrixIEAcellular_component
GO:0006418TRNA aminoacylation for protein translationTASbiological_process
GO:0006433Prolyl-tRNA aminoacylationIEAbiological_process
GO:0010467Gene expressionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33562165570.67068233730.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2439446092
GSE13712_SHEARDown-0.1873283439
GSE13712_STATICUp0.3557882343
GSE19018Up0.0714639466
GSE19899_A1Up0.0054472753
GSE19899_A2Up0.6467107411
PubMed_21979375_A1Down-0.1003064241
PubMed_21979375_A2Up0.4722792996
GSE35957Down-0.5892869837
GSE36640Down-0.1282921434
GSE54402Up0.1434932571
GSE9593Down-0.2617867299
GSE43922Up0.0858482109
GSE24585Down-0.0400126232
GSE37065Up0.0046532546
GSE28863_A1Up0.1713190394
GSE28863_A2Up0.2059310381
GSE28863_A3Down-0.1301495219
GSE28863_A4Down-0.1903358487
GSE48662Down-0.0268382499

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.