HCSGD entry for ABP1

1. General information

Official gene symbolABP1
Entrez ID26
Gene full nameamiloride binding protein 1 (amine oxidase (copper-containing))
Other gene symbolsABP AOC1 DAO DAO1 KAO
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityIDAmolecular_function
GO:0005261Cation channel activityIDAmolecular_function
GO:0005272Sodium channel activityTASmolecular_function
GO:0005507Copper ion bindingIDA IEAmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0005777PeroxisomeNAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005923Tight junctionISScellular_component
GO:0008131Primary amine oxidase activityIDA IEAmolecular_function
GO:0008144Drug bindingIDAmolecular_function
GO:0008201Heparin bindingIDAmolecular_function
GO:0008270Zinc ion bindingIDAmolecular_function
GO:0009308Amine metabolic processIEAbiological_process
GO:0032403Protein complex bindingIDAmolecular_function
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0035874Cellular response to copper ion starvationIDAbiological_process
GO:0042493Response to drugIDAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0046677Response to antibioticIDAbiological_process
GO:0048038Quinone bindingIDA IEAmolecular_function
GO:0052597Diamine oxidase activityIDAmolecular_function
GO:0052598Histamine oxidase activityIEAmolecular_function
GO:0052599Methylputrescine oxidase activityIEAmolecular_function
GO:0052600Propane-1,3-diamine oxidase activityIEAmolecular_function
GO:0055114Oxidation-reduction processIDAbiological_process
GO:0071280Cellular response to copper ionIDAbiological_process
GO:0071420Cellular response to histamineIDAbiological_process
GO:0071504Cellular response to heparinTASbiological_process
GO:0097185Cellular response to azideIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52753345620.92389808520.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0656577207
GSE13712_SHEARUp0.1483691610
GSE13712_STATICUp0.0763584764
GSE19018Up0.1098446943
GSE19899_A1Up0.0050287919
GSE19899_A2Up0.0642407996
PubMed_21979375_A1Down-0.0298452610
PubMed_21979375_A2Up0.1457133548
GSE35957Up0.1750528581
GSE36640Up0.1436819437
GSE54402Up0.0179070894
GSE9593Up0.1598241899
GSE43922Up0.0255676777
GSE24585Down-0.0646212056
GSE37065Up0.0835007640
GSE28863_A1Down-0.0807568059
GSE28863_A2Up0.1275897568
GSE28863_A3Up0.0600631104
GSE28863_A4Up0.0726353029
GSE48662Up0.0163305522

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AmilorideDB00594 APRD00790 | EXPT00514
DiminazeneDB03608 EXPT00754

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.