HCSGD entry for L3MBTL1

1. General information

Official gene symbolL3MBTL1
Entrez ID26013
Gene full namel(3)mbt-like 1 (Drosophila)
Other gene symbolsH-L(3)MBT L3MBTL ZC2HC3 dJ138B7.3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000785ChromatinIDAcellular_component
GO:0000793Condensed chromosomeIDAcellular_component
GO:0003682Chromatin bindingIDAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007088Regulation of mitosisIMPbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016568Chromatin modificationIDAbiological_process
GO:0030097HemopoiesisIEPbiological_process
GO:0031491Nucleosome bindingIDAmolecular_function
GO:0031493Nucleosomal histone bindingIDAmolecular_function
GO:0032093SAM domain bindingIPImolecular_function
GO:0035064Methylated histone residue bindingIDA IPImolecular_function
GO:0042393Histone bindingIPImolecular_function
GO:0042802Identical protein bindingIPImolecular_function
GO:0045652Regulation of megakaryocyte differentiationIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDA IMPbiological_process
GO:0051726Regulation of cell cycleNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86452909460.77408056680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0246126166
GSE13712_SHEARDown-0.0264502890
GSE13712_STATICUp0.0378816613
GSE19018Up0.0093487026
GSE19899_A1Up0.0830336176
GSE19899_A2Up0.0208385706
PubMed_21979375_A1Down-0.1569941213
PubMed_21979375_A2Down-0.1044938334
GSE35957Down-0.0224858999
GSE36640Up0.1439528721
GSE54402Down-0.0445451260
GSE9593Down-0.0526519015
GSE43922Up0.0274089756
GSE24585Down-0.0767579639
GSE37065Down-0.0071795534
GSE28863_A1Down-0.0086584967
GSE28863_A2Up0.0042230917
GSE28863_A3Up0.1793202345
GSE28863_A4Up0.0779996762
GSE48662Down-0.1612658187

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2-(N-Morpholino)-Ethanesulfonic AcidDB03814 EXPT02154

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.