HCSGD entry for OSBPL3
1. General information
| Official gene symbol | OSBPL3 |
|---|---|
| Entrez ID | 26031 |
| Gene full name | oxysterol binding protein-like 3 |
| Other gene symbols | ORP-3 ORP3 OSBP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006869 | Lipid transport | IEA | biological_process |
| GO:0015485 | Cholesterol binding | IDA | molecular_function |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
| GO:0097038 | Perinuclear endoplasmic reticulum | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0467012424 | 0.1838709586 | 0.4782970428 | 0.8315322171 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1139722016 |
| GSE13712_SHEAR | Up | 0.4079275268 |
| GSE13712_STATIC | Up | 0.9671384990 |
| GSE19018 | Up | 0.7463017661 |
| GSE19899_A1 | Down | -0.0249435569 |
| GSE19899_A2 | Down | -0.7319728985 |
| PubMed_21979375_A1 | Down | -1.3709726125 |
| PubMed_21979375_A2 | Up | 0.1076389751 |
| GSE35957 | Up | 0.3527298470 |
| GSE36640 | Up | 0.2365318410 |
| GSE54402 | Down | -1.0562985295 |
| GSE9593 | Up | 0.6959811350 |
| GSE43922 | Down | -0.5616968168 |
| GSE24585 | Down | -0.1740587392 |
| GSE37065 | Up | 0.3410948731 |
| GSE28863_A1 | Up | 0.2680249155 |
| GSE28863_A2 | Up | 0.6644320349 |
| GSE28863_A3 | Down | -0.5829736572 |
| GSE28863_A4 | Down | -0.0260900371 |
| GSE48662 | Up | 0.0674869181 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027159 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030982 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031915 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031915 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
