HCSGD entry for LRRC32

1. General information

Official gene symbolLRRC32
Entrez ID2615
Gene full nameleucine rich repeat containing 32
Other gene symbolsD11S833E GARP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002755MyD88-dependent toll-like receptor signaling pathwayIEAbiological_process
GO:0004888Transmembrane signaling receptor activityIEAmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0009617Response to bacteriumIEAbiological_process
GO:0010628Positive regulation of gene expressionIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0034170Toll-like receptor 11 signaling pathwayIEAbiological_process
GO:0045087Innate immune responseIEAbiological_process
GO:0046007Negative regulation of activated T cell proliferationIEAbiological_process
GO:0050710Negative regulation of cytokine secretionIEAbiological_process
GO:0050729Positive regulation of inflammatory responseIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23105556020.16826975420.91467525560.7930220591

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1396535463
GSE13712_SHEARDown-0.5906370494
GSE13712_STATICDown-0.2030598180
GSE19018Down-0.2432942568
GSE19899_A1Down-0.0171922706
GSE19899_A2Up0.0828425243
PubMed_21979375_A1Down-1.0158803682
PubMed_21979375_A2Down-0.0017295166
GSE35957Up0.8393797410
GSE36640Down-0.2475132550
GSE54402Up0.1090864877
GSE9593Up2.1025642910
GSE43922Down-0.5853214752
GSE24585Up0.2895841745
GSE37065Down-0.1086161641
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.4708351203

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017818MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.