HCSGD entry for STEAP2
1. General information
| Official gene symbol | STEAP2 |
|---|---|
| Entrez ID | 261729 |
| Gene full name | STEAP family member 2, metalloreductase |
| Other gene symbols | IPCA1 PCANAP1 PUMPCn STAMP1 STMP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | IDA | molecular_function |
| GO:0005769 | Early endosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006811 | Ion transport | IEA | biological_process |
| GO:0006893 | Golgi to plasma membrane transport | IDA | biological_process |
| GO:0006897 | Endocytosis | IDA | biological_process |
| GO:0009725 | Response to hormone | IDA | biological_process |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0030140 | Trans-Golgi network transport vesicle | IDA | cellular_component |
| GO:0030173 | Integral component of Golgi membrane | IDA | cellular_component |
| GO:0045055 | Regulated secretory pathway | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055072 | Iron ion homeostasis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0616648038 | 0.0949853881 | 0.5383347595 | 0.5874319549 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5423848558 |
| GSE13712_SHEAR | Down | -0.7948616883 |
| GSE13712_STATIC | Down | -0.7368132950 |
| GSE19018 | Down | -0.1079447167 |
| GSE19899_A1 | Up | 0.0351424949 |
| GSE19899_A2 | Up | 0.4976005265 |
| PubMed_21979375_A1 | Up | 0.0768527750 |
| PubMed_21979375_A2 | Down | -0.3889197696 |
| GSE35957 | Up | 1.3307479519 |
| GSE36640 | Down | -0.4265085269 |
| GSE54402 | Up | 1.7345907855 |
| GSE9593 | Up | 0.1252377950 |
| GSE43922 | Up | 0.0036768672 |
| GSE24585 | Down | -0.0597110326 |
| GSE37065 | Up | 0.2042262113 |
| GSE28863_A1 | Up | 0.1497060585 |
| GSE28863_A2 | Up | 0.8851381693 |
| GSE28863_A3 | Down | -0.4343255126 |
| GSE28863_A4 | Down | -0.4317403346 |
| GSE48662 | Up | 0.0628429127 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031189 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-940 | MIMAT0004983 | MIRT036587 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048078 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
