HCSGD entry for GAS1

1. General information

Official gene symbolGAS1
Entrez ID2619
Gene full namegrowth arrest-specific 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002053Positive regulation of mesenchymal cell proliferationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDAcellular_component
GO:0007050Cell cycle arrestIEAbiological_process
GO:0007411Axon guidanceIEAbiological_process
GO:0008589Regulation of smoothened signaling pathwayISSbiological_process
GO:0010955Negative regulation of protein processingIMPbiological_process
GO:0012501Programmed cell deathIEAbiological_process
GO:0016021Integral component of membraneNAScellular_component
GO:0021587Cerebellum morphogenesisIEAbiological_process
GO:0021904Dorsal/ventral neural tube patterningIEAbiological_process
GO:0030308Negative regulation of cell growthIEAbiological_process
GO:0035924Cellular response to vascular endothelial growth factor stimulusIEPbiological_process
GO:0042473Outer ear morphogenesisIEAbiological_process
GO:0042474Middle ear morphogenesisIEAbiological_process
GO:0042476OdontogenesisIEAbiological_process
GO:0042733Embryonic digit morphogenesisIEAbiological_process
GO:0042981Regulation of apoptotic processISSbiological_process
GO:0043010Camera-type eye developmentIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0045165Cell fate commitmentISSbiological_process
GO:0045879Negative regulation of smoothened signaling pathwayIEAbiological_process
GO:0045880Positive regulation of smoothened signaling pathwayIEAbiological_process
GO:0045930Negative regulation of mitotic cell cycleIDA IGIbiological_process
GO:0046658Anchored component of plasma membraneISScellular_component
GO:0048589Developmental growthISSbiological_process
GO:0048592Eye morphogenesisIEAbiological_process
GO:0048701Embryonic cranial skeleton morphogenesisIEAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0050680Negative regulation of epithelial cell proliferationIEAbiological_process
GO:0060021Palate developmentIEAbiological_process
GO:0060628Regulation of ER to Golgi vesicle-mediated transportIMPbiological_process
GO:2001240Negative regulation of extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90542105160.00747817710.99999024730.1729640598

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2128990286
GSE13712_SHEARDown-0.1180985356
GSE13712_STATICDown-0.0853854573
GSE19018Down-0.3493261506
GSE19899_A1Down-0.4483322872
GSE19899_A2Down-0.7940526121
PubMed_21979375_A1Down-1.0025207993
PubMed_21979375_A2Down-1.1440938772
GSE35957Up0.7624955552
GSE36640Down-0.8730809689
GSE54402Down-0.7048702932
GSE9593Down-0.6364490391
GSE43922Up0.1624120823
GSE24585Down-0.1724776164
GSE37065Down-0.1408226414
GSE28863_A1Up0.1786773271
GSE28863_A2Up0.0259441743
GSE28863_A3Up0.1789289967
GSE28863_A4Down-0.0136067979
GSE48662Down-0.4495501001

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-130b-3pMIMAT0000691MIRT020112SequencingFunctional MTI (Weak)20371350
hsa-miR-183-5pMIMAT0000261MIRT025001SequencingFunctional MTI (Weak)20371350
hsa-miR-34a-5pMIMAT0000255MIRT025257SequencingFunctional MTI (Weak)20371350
hsa-miR-148a-3pMIMAT0000243MIRT025983SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.