HCSGD entry for TIAM2

1. General information

Official gene symbolTIAM2
Entrez ID26230
Gene full nameT-cell lymphoma invasion and metastasis 2
Other gene symbolsSTEF TIAM-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005057Receptor signaling protein activityIEAmolecular_function
GO:0005085Guanyl-nucleotide exchange factor activityIEA TASmolecular_function
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030027LamellipodiumIEAcellular_component
GO:0030175FilopodiumIEAcellular_component
GO:0030426Growth coneIEAcellular_component
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10515663540.70760703240.67360131421.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1699828583
GSE13712_SHEARUp0.3360651503
GSE13712_STATICUp0.2536883492
GSE19018Up0.6431146921
GSE19899_A1Up0.1540666390
GSE19899_A2Up0.0544616185
PubMed_21979375_A1Up0.6670203844
PubMed_21979375_A2Down-0.1887863069
GSE35957Down-0.4751635566
GSE36640Down-0.1571415010
GSE54402Up0.1450797356
GSE9593Up0.1743440421
GSE43922Down-0.3532590747
GSE24585Down-0.0223061311
GSE37065Up0.3279326208
GSE28863_A1Up0.3136879100
GSE28863_A2Up0.4397457605
GSE28863_A3Up0.3348431118
GSE28863_A4Down-0.1905885259
GSE48662Down-0.0770385927

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.