HCSGD entry for FBXO6
1. General information
| Official gene symbol | FBXO6 |
|---|---|
| Entrez ID | 26270 |
| Gene full name | F-box protein 6 |
| Other gene symbols | FBG2 FBS2 FBX6 Fbx6b |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000077 | DNA damage checkpoint | TAS | biological_process |
| GO:0001948 | Glycoprotein binding | ISS | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0006508 | Proteolysis | TAS | biological_process |
| GO:0006516 | Glycoprotein catabolic process | IEA | biological_process |
| GO:0006986 | Response to unfolded protein | IEA | biological_process |
| GO:0019005 | SCF ubiquitin ligase complex | IDA | cellular_component |
| GO:0030163 | Protein catabolic process | IEA | biological_process |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process | ISS | biological_process |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0119954029 | 0.6328814559 | 0.2739097920 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6510177399 |
| GSE13712_SHEAR | Up | 1.4714972273 |
| GSE13712_STATIC | Up | 1.7407594773 |
| GSE19018 | Up | 0.2333244883 |
| GSE19899_A1 | Down | -0.4578149391 |
| GSE19899_A2 | Up | 0.2731113447 |
| PubMed_21979375_A1 | Up | 0.9390483621 |
| PubMed_21979375_A2 | Down | -0.2065630934 |
| GSE35957 | Down | -0.3732506534 |
| GSE36640 | Up | 0.7126195620 |
| GSE54402 | Down | -0.0492124149 |
| GSE9593 | Up | 1.1954046651 |
| GSE43922 | Up | 0.0725048358 |
| GSE24585 | Up | 0.3183151661 |
| GSE37065 | Up | 0.4037313819 |
| GSE28863_A1 | Down | -0.3893139021 |
| GSE28863_A2 | Down | -0.2147592991 |
| GSE28863_A3 | Down | -0.0698291080 |
| GSE28863_A4 | Down | -0.2006691287 |
| GSE48662 | Up | 0.2558545876 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
