HCSGD entry for PCOLCE2
1. General information
| Official gene symbol | PCOLCE2 |
|---|---|
| Entrez ID | 26577 |
| Gene full name | procollagen C-endopeptidase enhancer 2 |
| Other gene symbols | PCPE2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005518 | Collagen binding | IDA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0008201 | Heparin binding | IDA | molecular_function |
| GO:0010952 | Positive regulation of peptidase activity | IDA | biological_process |
| GO:0016504 | Peptidase activator activity | IDA | molecular_function |
| GO:0043085 | Positive regulation of catalytic activity | IDA | biological_process |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
| GO:0052547 | Regulation of peptidase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4905460051 | 0.0210223624 | 0.9999902473 | 0.2805931034 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2176748281 |
| GSE13712_SHEAR | Up | 0.0196270969 |
| GSE13712_STATIC | Down | -0.2164060598 |
| GSE19018 | Down | -0.0800417876 |
| GSE19899_A1 | Down | -0.1837424416 |
| GSE19899_A2 | Down | -0.4329138331 |
| PubMed_21979375_A1 | Down | -1.5741242658 |
| PubMed_21979375_A2 | Down | -0.7834777630 |
| GSE35957 | Up | 0.3246321322 |
| GSE36640 | Down | -1.6783112246 |
| GSE54402 | Down | -1.1537066844 |
| GSE9593 | Up | 0.5211150985 |
| GSE43922 | Down | -0.0135191673 |
| GSE24585 | Up | 0.0622731921 |
| GSE37065 | Up | 0.6340751986 |
| GSE28863_A1 | Up | 0.5058562670 |
| GSE28863_A2 | Down | -0.3367627440 |
| GSE28863_A3 | Down | -0.1609324674 |
| GSE28863_A4 | Up | 0.0173048205 |
| GSE48662 | Down | -0.0755183066 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024608 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026916 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030184 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-182-5p | MIMAT0000259 | MIRT047213 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
