HCSGD entry for FOXD3

1. General information

Official gene symbolFOXD3
Entrez ID27022
Gene full nameforkhead box D3
Other gene symbolsAIS1 Genesis HFH2 VAMAS2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDA ISSbiological_process
GO:0000790Nuclear chromatinIDAcellular_component
GO:0000977RNA polymerase II regulatory region sequence-specific DNA bindingIDAmolecular_function
GO:0001227RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptionIDAmolecular_function
GO:0001658Branching involved in ureteric bud morphogenesisIBAbiological_process
GO:0001701In utero embryonic developmentISSbiological_process
GO:0001755Neural crest cell migrationIBAbiological_process
GO:0001822Kidney developmentIBAbiological_process
GO:0001829Trophectodermal cell differentiationIBAbiological_process
GO:0001892Embryonic placenta developmentIBAbiological_process
GO:0003690Double-stranded DNA bindingIBAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityISSmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005667Transcription factor complexIBAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIBA IDAbiological_process
GO:0007389Pattern specification processIBAbiological_process
GO:0007422Peripheral nervous system developmentIBAbiological_process
GO:0008134Transcription factor bindingIBAmolecular_function
GO:0008301DNA binding, bendingIBAmolecular_function
GO:0030318Melanocyte differentiationIBAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0048484Enteric nervous system developmentIBAbiological_process
GO:0048485Sympathetic nervous system developmentIBAbiological_process
GO:0048846Axon extension involved in axon guidanceIBAbiological_process
GO:0048937Lateral line nerve glial cell developmentIBAbiological_process
GO:0050935Iridophore differentiationIBAbiological_process
GO:0051090Regulation of sequence-specific DNA binding transcription factor activityIBAbiological_process
GO:0051216Cartilage developmentIBAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62231446370.87126053720.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0660867450
GSE13712_SHEARUp0.0405591872
GSE13712_STATICUp0.0000514957
GSE19018Up0.1258344771
GSE19899_A1Down-0.0430534487
GSE19899_A2Down-0.0649938342
PubMed_21979375_A1Up0.2303746129
PubMed_21979375_A2Down-0.1486473928
GSE35957Up0.0399082110
GSE36640Up0.0920569763
GSE54402Up0.0556728720
GSE9593Up0.1226701163
GSE43922Up0.0377930770
GSE24585Down-0.0984856572
GSE37065Down-0.0282456708
GSE28863_A1Down-0.0571665298
GSE28863_A2Up0.1672251533
GSE28863_A3Up0.3879309749
GSE28863_A4Up0.0876579299
GSE48662Down-0.0449453523

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017622MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.