HCSGD entry for ZBTB32


1. General information

Official gene symbolZBTB32
Entrez ID27033
Gene full namezinc finger and BTB domain containing 32
Other gene symbolsFAXF FAZF Rog TZFP ZNF538
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0000228Nuclear chromosomeIEAcellular_component
GO:0001817Regulation of cytokine productionIEAbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003677DNA bindingISSmolecular_function
GO:0003714Transcription corepressor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusTAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006281DNA repairTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0008270Zinc ion bindingISSmolecular_function
GO:0030097HemopoiesisIEAbiological_process
GO:0042098T cell proliferationIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66633533680.48624551500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2041291766
GSE13712_SHEARDown-0.1213073023
GSE13712_STATICDown-0.1688863952
GSE19018Down-0.1013097977
GSE19899_A1Down-0.0222670838
GSE19899_A2Up0.0276450588
PubMed_21979375_A1Up0.4237292450
PubMed_21979375_A2Down-0.1942510913
GSE35957Up0.0983558124
GSE36640Up0.1882159136
GSE54402Up0.0268410872
GSE9593Up0.1987235008
GSE43922Up0.0326483717
GSE24585Down-0.0319755676
GSE37065Up0.4824201043
GSE28863_A1Down-0.2754815705
GSE28863_A2Down-0.2845567908
GSE28863_A3Up0.3708438708
GSE28863_A4Down-0.0409767285
GSE48662Up0.1925458919

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019205MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.