HCSGD entry for NDOR1
1. General information
| Official gene symbol | NDOR1 |
|---|---|
| Entrez ID | 27158 |
| Gene full name | NADPH dependent diflavin oxidoreductase 1 |
| Other gene symbols | NR1 bA350O14.9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003958 | NADPH-hemoprotein reductase activity | IBA | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0008219 | Cell death | IDA | biological_process |
| GO:0010181 | FMN binding | IDA IEA | molecular_function |
| GO:0016491 | Oxidoreductase activity | IDA IEA | molecular_function |
| GO:0016709 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | IBA | molecular_function |
| GO:0036245 | Cellular response to menadione | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045111 | Intermediate filament cytoskeleton | IDA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0050660 | Flavin adenine dinucleotide binding | IDA | molecular_function |
| GO:0050661 | NADP binding | IDA | molecular_function |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3790673683 | 0.8355479199 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1649216627 |
| GSE13712_SHEAR | Up | 0.0569524732 |
| GSE13712_STATIC | Up | 0.0274105302 |
| GSE19018 | Up | 0.0766207430 |
| GSE19899_A1 | Down | -0.1492658925 |
| GSE19899_A2 | Up | 0.0277079553 |
| PubMed_21979375_A1 | Down | -0.1312387293 |
| PubMed_21979375_A2 | Down | -0.1571429730 |
| GSE35957 | Up | 0.1509564137 |
| GSE36640 | Down | -0.1435621501 |
| GSE54402 | Down | -0.0067279787 |
| GSE9593 | Down | -0.0262259872 |
| GSE43922 | Up | 0.1433356289 |
| GSE24585 | Down | -0.0249867893 |
| GSE37065 | Down | -0.0195553549 |
| GSE28863_A1 | Up | 0.2574302223 |
| GSE28863_A2 | Up | 0.4124684578 |
| GSE28863_A3 | Up | 0.4324593101 |
| GSE28863_A4 | Up | 0.2256501428 |
| GSE48662 | Up | 0.1082623143 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040948 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045962 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
